DW-1002

Brilliant Blue G-250 (BBG250) is an ophthalmic surgical adjuvant whose active ingredient is a dye with high staining ability.
The dye temporarily and safely stains the capsule protecting the inner limiting membrane or crystalline lens in the back of the eye, making it easier to perform vitreous or cataract surgery.
BBG250 was discovered by a research group at Kyushu University, and has since been commercialized. DWTI acquired the business from Healios K.K. in 2017, and we have since been developing the dye under exclusive license from Kyushu University.

We have granted an exclusive sublicense for DW-1002 for all regions worldwide outside Japan to Dutch Ophthalmic Research Center (International) B.V. (DORC), which has been manufacturing and selling the product in Europe and other countries since September 2010.
Wakamoto Pharmaceutical Co., Ltd. has been granted an exclusive sublicense for Japan, and is moving forward with development aiming to obtain approval.

①ILM peeling
in Europe,U.S.
and Canada
②ILM staining
in Japan
③Cataract surgery
in Japan
Clinical indication ①ILM peeling (Europe,U.S. and Canada)
②ILM staining (Japan)
③Cataract surgery (Japan)
Development process ①Launched (Europe,U.S. and Canada)
②Phase III clinical trials (Japan) completed
③Phase III clinical trials (Japan) completed
Licensee ①Dutch Ophthalmic Research Center International B.V(DORC)
②③Wakamoto Pharmaceutical Co., Ltd.

Development Progress

  • 2021.10
    Launched (Canada)
  • 2021.01
    Approved of new drug application (Canada)
  • 2020.04
    Launched (U.S.)
  • 2017.04
    Acquired of business related to the ophthalmic surgical adjuvant
  • 2010.09
    Launched (Europe)